3 Steps to Identify Supplements that Lack Scientific Evidence

You read about a supplement that allegedly "Boostsbeneficial health effects on human beings. Only
your mood and motivation!" That sure sounds good soresearch with human subjects, using randomized
your surf over to the company's web site.The webcontrolled trials, can offer such evidence.On the
site looks official--it's even got footnotes citing scientificPubMed.org search page, click on the "Limits" tab
journals. You're ready to purchase the supplementlocated under the "Search" box. You will see a number
online until you ask yourself, "What if this supplementof drop-down menus. First click on the Publication
doesn't really possess any scientific evidence for itsType menu and then select Randomized Controlled
efficacy? How can I tell the difference betweenTrial. Next click on the drop-down menu labeled,
supplements with solid evidence for their reportedHumans or Animals and click on Humans.An
benefits versus those lacking any scientificExampleMorinda citrifolia is the scientific name for a
support?"Here are the 3 Steps to answer thosepopular ingredient in a nutritional supplement. First
questions:Step 1: Go to is a National Library of Medicinesearch on PubMed for Morinda citrifolia, without placing
(United States) web site where you can search forLimits on your search.How many results did you
articles published in peer-reviewed scientificreceive?The count was 69 at the time I wrote this
journals.Why check PubMed? Because the Nationalarticle. Looks impressive, huh?But now search for
Library of Medicine carefully selects only high-qualityMorinda citrifolia after first placing Limits on the search
journals that offer value to medical scientists aroundas described above, so that you receive only those
the world. Selection criteria are detailed on this webstudies which provide more definitive scientific
page: 2: Once on the PubMed web site, search forevidence for the positive effects of Morinda
research articles using the generic (scientific) name ofcitrifolia.How many journal articles did you find
the supplement in question. Supplement manufacturerssearching with the specified limits? I found 1. Thus, out
must list the scientific name for their supplement'sof 69 articles found on PubMed.org, only one provides
ingredients on the label and in advertisements.some evidence forMorinda citrifolia's beneficial
Supplements often contain many ingredients but usuallyeffects.It's great that this study exists because it could
only a few provide the purported benefits. Those areend up being one of several studies demonstrating that
the ingredients you want to evaluate--they are oftenMorinda citrifolia provides health benefits. However, at
the same ones the manufacturer highlights inthe present time, the most one could say about
advertisements.Step 3: This is the step someMorinda citrifolia is something like, "One study has
supplement companies don't want you to know.provided very preliminary evidence of Morinda
Before you click on the "Search" button at PubMed.org,citrifolia's health benefits with a narrowly defined
limit your search to studies that utilize the rightpatient group. Further controlled trials are needed to
research methodology with the right population.Thedetermine if this result will be replicated by other
right research methodology is a randomized controlledresearch groups working with different
trial (the double-blind, placebo control group design fitspopulations."ConclusionBy using the "Limits" function on
under this category) and the right population is humanthe PubMed.org search menu, consumers can identify
beings.Specifying human subjects is important becausesupplements that lack scientific evidence for their
you want to know if the ingredients in a supplementefficacy.Mark Worthen, Psy.D. is a Phi Betta Kappa
have been shown to produce the advertised benefitsgraduate of the University of Maryland's Honors
in real live human beings--not just in rats pressingPsychology program. He was a Clinical Fellow,
levers for food pellets or in a "case study" with oneDepartment of Psychiatry, Harvard Medical School and
person.This is not to say that basic science research,earned his Doctor of Psychology degree from Baylor
which is often conducted initially with animals, isUniversity in 1990. In addition to his work as a
unimportant. On the contrary, such research usuallypsychologist, he is an independent representative for a
serves as a crucial building block for subsequent clinicalleading health and wellness company and owner of
research with humans. But basic science researchBest-Mlm-Opportunities.
does not provide scientific evidence for a supplement's