Aicardi Syndrome

It is a disorder that is categorized by the partial orexpiration.
complete malfunction of the corpus callosum, a brainThe neurological disorder was first diagnosed more
structure linking two hemispheres inside it. Aicardithan thirty years ago, when French doctor, Dr. Jean
syndrome often causes childhood seizure (intantileDennis Aicardi, identified eight children who continually
spasms), eye abnormality or lesions of the retina, andexperience infantile spasms. The doctor believed the
metal retardation. Aicardi Syndrome is also linked tosyndrome was caused by a deficiency in the female
microcephaly, a brain defect; microgyria, where bumpschromosome (X). Hence, the disorder only affects
inside the brain tend to be narrow; or porecenphalicmajority of female infants, although there is one
cysts, a brain condition causing fluids to fill the gaps inreported case of a baby boy diagnosed with the
the brain. Further studies also indicate that a fewsyndrome. Currently, there are about 500 reported
abnormalities may include a cleft lip and vertebral bodycases worldwide, with only one case of siblings
malfunction.afflicted with the condition. Therefore it is believed that
It is children, between three to five months, who arethe disorder is a new mutation and not all of the family
most often branded with Aicardi Syndrome. Thesemembers may carry the defective gene
children are results of normal births, but haveThere is currently no cure for Aicardi Syndrome. A
developed the abnormality as soon as theysymptomatic treatment may be recommended to
experience brain spasms. Infantile spasms at this agemanage the seizures, usually in the form of anti-seizure
causes neural synapses to close, thereby inhibiting themedicines. A few intervention programs to manage
babies' brain development. Hence, most cases havemental retardation are also administered. Physical and
moderate to very severe degrees of retardation. Anoccupational therapy may also be recommended to
infant afflicted with the syndrome may alsoaid the child in her development. The life expectancy
experience delays in development. They could alsofor an infant afflicted with Aicardi syndrome is
have difficulty when it comes to respiratory infectionsdependent on how severe the condition is.
like pneumonia and this could consequently cause their