Will Niacin Cure Mental Illness?

Since a deficiency of vitamin B3 or niacin causesconsumer advocate and board member of the
pellagra which is characterized by mental disturbances,National Council Against Health Fraud Inc. (NCAHF) in
practitioners of orthomolecular medicine or“Health Schemes, Scams and Frauds” published
megavitamin advocates believe that large doses ofby Consumer Reports Books.
niacin can treat schizophrenia.Another vitamin that’s being abused by
A careful review made by the American Psychiatricmegavitamin proponents is vitamin B6 (pyridoxine)
Association in the 1970s showed that this was not thewhich is being prescribed for premenstrual syndrome
case and it has deplored this practice. Later, the(PMS). This refers to a set of symptoms that begin
Research Advisory Committee of the U.S. Nationalseven to 14 days prior to menstruation. Such
Institute of Mental Health and the Canadian Mentalsymptoms include nervousness and irritability, dizziness,
Health Association followed suit after studying theemotional instability, headaches, bloating, diarrhea, and
claims made by orthomolecular psychiatrists.tender, swollen breasts which have been linked to
"Scientific evaluation of nicotinic acid as a treatmenthormone changes in the body during menstruation.
for schizophrenia concludes that improvement claimedOrthomolecular advocates think this can be prevented
by purveyors of the megavitamin therapies resultedby taking massive doses of vitamin B6 in spite of the
not from the vitamins but from the conventionalfact that no conclusive evidence exists supporting this
therapy (drugs and/or psychotherapy) given at thepractice. Furthermore, the risks far outweigh the
same time," said Drs. Harold M. Silverman, Joseph A.potential benefits of pyridoxine supplementation.
Romano and Garry Elmer in “The Vitamin Book: A"During the past few years, medical journals have
No-Nonsense Consumer Guide.”reported more than 100 cases of toxicity from B6
Niacin is also being promoted as a cure for highsupplementation, resulting in a condition called peripheral
cholesterol levels. While this is true under close medicalneuritis. The reported symptoms, some of which
supervision, self-medication and the unrealisticresembled those of multiple sclerosis, included
recommendations of orthomolecular advocates cannumbness and tingling in the hands, difficulty in walking,
have disastrous results on your health.and electric shocks shooting down the spine,”
"Troublesome side effects often occur, mostBarrett revealed.
commonly the 'niacin flush' -- intense reddening and"Many medications and techniques have been tried for
itching of the face and upper body that usuallyPMS -- ranging from megavitamins to biofeedback --
diminishes after several weeks. High-dose niacin canbut none has had much success. A possible reason is
also cause gastrointestinal upset, abnormal liverthat more than 150 different symptoms have been
function tests, elevated blood-sugar levels and, rarely,associated with PMS. Despite a fair amount of clinical
aerial fibrillation (rapid beating of the heart)," said Dr.investigation, its cause remains unclear," he added.
Stephen Barrett, a psychiatrist, prize-winning author,(Next: Will vitamin B12 give you energy?