Panic Attacks May Be More Dangerous For Women - Texas Universities Could Find Answers

Suffering a panic attack may increase a woman's riskexhibit four of twelve specific symptoms,
of heart attack and stroke by as much as threeaccompanied by a sudden onset of fear, anxiety, or
hundred percent. Previous studies have linkeddiscomfort, according to the Diagnostic and Statistical
depression with heart disease and other medicalManual of Mental Disorders. But further testing is often
conditions, according to the University of Texasrequired in order to determine what a patient is actually
Medical Branch, but a recent analysis published in theexperiencing. Such sensations could be the result of a
Archives of General Psychiatry is one of the first topanic attack...or a potentially deadly heart attack.
independently link anxiety-related disorders withCould individuals, then, who have been diagnosed with
cardiovascular problems.anxiety disorders or panic attacks be experiencing
Dr. Jordan Smoller of Boston's Massachusetts Generalheart problems? Could heart patients be neglecting
Hospital, and colleagues, followed more than 3,000anxiety issues? Could they be interdependent? Such
women aged fifty-one to eighty-three for five years. Inscenarios are entirely possible, and the health insurance
that time, 330 reported having a full-blown panic attack,and health care industries must decide how to properly
and four percent experienced either a heart attack --diagnose and handle these cases. So, too, must
otherwise known as a mild cardio-infarction (MI) -- ormedical researchers now determine the extent of their
stroke. Only two percent of the subjects who did notrelationship. What if one spurs the other? Should panic
suffer a panic attack still experienced one or the otherattacks, then, in some cases, be considered
event.part-and-parcel of certain cardiovascular problems? Or
After controlling for variables, such as smoking, highthe other way around? Major research centers, like
blood pressure, inactivity and depression, Smoller andthose located in Dallas, Houston, and Austin, may play
colleagues concluded that women who reporteda pivotal role in years to come in answering such
full-blown panic attacks were three times as likely toquestions.
suffer a MI or stroke within five years. Smoller"One study doesn't settle [the] question. The number of
speculated panic attacks may trigger heart rhythmevents seen in this sample is still relatively small," said
problems or release stress hormones that may harmSmoller.
the organ. Laura Kubzansky of the Harvard School ofSmoller's study is not without its opponents, however.
Public Health, who was not involved with the study butThe research, conducted between 1997 and 2000,
conducts comparable research, produced a similarwas funded by GloxoWelcome (now GlaxoSmithKline
theory. Stress hormones, she said, may causePLC), which manufacturers the anti-anxiety drug Paxil.
immediate damage to the heart, or wear-and-tearSome co-authors also reported financial ties with the
over time.company.
"...the body is flooded with hormones that in the shortDr. JoAnn Manson, of Harvard University's Brigham
run help the body cope with the emergency, but in theand Women's Hospital, contested aspects of Smoller's
long run take a toll," said Kubzansky. "We still don'tresearch on other grounds. Manson believes the
know how best to address this or how reversiblestudy's reliance on subjects' personal accounts of
these effects are." Both doctors caution that furtherevents, rather than on doctors' analyses, may also be
research is necessary.a weakness. Still, she said, the study highlights what
Smoller's study could have serious implications for thecould be a very real connection between panic
health care and health insurance industries. Symptomsattacks and cardiovascular issues.
related to panic attacks and other anxiety-related"It does tie together very well with what we know
disorders often mimic sensations produced byabout the biology and physiology of the stress
cardiovascular problems -- palpitations, pounding heart,hormones," said Manson. "I think it does suggest that
sweating, accelerated heart rate, chest pain, nausea,this is something [women prone to panic attacks
tingling, chills, and hot flashes, to name a few. In ordershould] discuss with [their] doctor[s].
to be classified as a "panic attack," an individual must